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Academic Journal

The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.

  • Authors : Duran P; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, New York, USA.; Loya-López S

Subjects: Calcium Channels, T-Type*/Calcium Channels, T-Type*/Calcium Channels, T-Type*/metabolism ; Voltage-Gated Sodium Channels*/Voltage-Gated Sodium Channels*/Voltage-Gated Sodium Channels*/metabolism; Mice

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 May; Vol. 180 (9), pp. 1267-1285. Date of Electronic Publication: 2023 Jan 15.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Constitutive activity of the dopamine (D 5 ) receptor, highly expressed in CA1 hippocampal neurons, selectively reduces Ca V 3.2 and Ca V 3.3 currents.

  • Authors : Mustafá ER; Electrophysiology Laboratory of the Multidisciplinary Institute of Cell Biology [Argentine Research Council (CONICET), Scientific Research Commission of the Province of Buenos Aires (CIC-PBA) and National University of La Plata (UNLP)], Buenos Aires, Argentina.; McCarthy CI

Subjects: Dopamine* ; Receptors, Dopamine D1*/Receptors, Dopamine D1*/Receptors, Dopamine D1*/metabolism; Animals

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 May; Vol. 180 (9), pp. 1210-1231. Date of Electronic Publication: 2023 Jan 02.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Mitophagy and endoplasmic reticulum-phagy accelerated by a p62 ZZ ligand alleviates paracetamol-induced hepatotoxicity.

  • Authors : Kim HY; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.; Yoon HS

Subjects: Acetaminophen*/Acetaminophen*/Acetaminophen*/toxicity ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/drug therapy ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/metabolism

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 May; Vol. 180 (9), pp. 1247-1266. Date of Electronic Publication: 2023 Jan 10.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Non-neuronal TRPA1 encodes mechanical allodynia associated with neurogenic inflammation and partial nerve injury in rats.

  • Authors : De Logu F; Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Florence, Florence, Italy.; De Siena G

Subjects: Transient Receptor Potential Channels* ; Peripheral Nervous System Diseases*; Humans

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 May; Vol. 180 (9), pp. 1232-1246. Date of Electronic Publication: 2023 Jan 07.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.

  • Authors : Zhao J; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.; Bai D

Subjects: Hepatic Stellate Cells* ; Flavonoids*/Flavonoids*/Flavonoids*/pharmacology; Mice

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1072-1089. Date of Electronic Publication: 2022 Dec 20.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Central metabolism as a potential origin of sex differences in morphine antinociception but not induction of antinociceptive tolerance in mice.

  • Authors : Gabel F; CNRS UPR3212, Institut des Neurosciences Cellulaires et Intégratives, Centre National de la Recherche Scientifique and University of Strasbourg, Strasbourg, France.; Hovhannisyan V

Subjects: Morphine* ; Tandem Mass Spectrometry*; Mice

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (7), pp. 843-861. Date of Electronic Publication: 2022 Feb 08.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

In vitro effects of eslicarbazepine (S-licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders.

  • Authors : Bayraktar E; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Department of Medical Pharmacology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Subjects: Epilepsy*/Epilepsy*/Epilepsy*/drug therapy ; Epilepsy*/Epilepsy*/Epilepsy*/genetics ; Dibenzazepines*/Dibenzazepines*/Dibenzazepines*/therapeutic use

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1038-1055. Date of Electronic Publication: 2022 Dec 19.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors.

  • Authors : Ruiz-Cantero MC; Department of Pharmacology, Faculty of Medicine, University of Granada, Granada, Spain.; Institute of Neuroscience, Biomedical Research Center, University of Granada, Granada, Spain.

Subjects: Nociceptors*/Nociceptors*/Nociceptors*/metabolism ; Analgesia*; Mice

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1148-1167. Date of Electronic Publication: 2022 Dec 29.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Curaxin CBL0137 inhibits endothelial inflammation and atherogenesis via suppression of the Src-YAP signalling axis.

  • Authors : Ding H; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Jiang M

Subjects: Endothelial Cells* ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/drug therapy; Animals

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1168-1185. Date of Electronic Publication: 2022 Dec 29.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Asymmetric activation of microglia in the hippocampus drives anxiodepressive consequences of trigeminal neuralgia in rodents.

  • Authors : Chen LQ; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, Institutes of Brain Science, Fudan University, Shanghai, China.; Lv XJ

Subjects: Trigeminal Neuralgia*/Trigeminal Neuralgia*/Trigeminal Neuralgia*/pathology ; Neuralgia*; Mice

  • Source: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1090-1113. Date of Electronic Publication: 2022 Dec 23.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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